pentobarbital will lower the extent or influence of nitrendipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.
pentobarbital will reduce the extent or result of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the level or result of quinidine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the level or influence of duvelisib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration with a powerful CYP3A inducer decreases duvelisib area underneath the curve (AUC), which may reduce duvelisib efficacy.
Contraindicated (1)pentobarbital will lower the level or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers can lead to lowered serum concentrations and loss of antimalarial efficacy
pentobarbital will minimize the level or influence of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Robust or reasonable CYP3A4 inducers may well enhance charge of diazepam elimination; therefore, efficacy of diazepam might be lessened.
Drugs which have step therapy connected to Every single prescription. This restriction ordinarily needs that selected requirements be achieved prior to acceptance to the prescription.
pentobarbital will lower the extent or influence of bazedoxifene/conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital increases toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers may enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will lower the extent or effect of tramadol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Decreased AUC of tramadol along with the Lively metabolite (O-desmethyltramadol) when coadministered with potent CYP3A4 and CYP2B6 inducers
pentobarbital raises effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Observe. Coadministration of ifosfamide with CYP2B6 inducers may perhaps raise metabolism of ifosfamide to its metabolite. Keep an eye on for elevated effects/toxicities if combined with CYP2B6 inducers.
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pentobarbital will lessen the level or outcome of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will click here lower the extent or influence of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Solid or average CYP3A4 inducers could increase level of diazepam elimination; thus, efficacy of diazepam can be decreased.